Potential drug interactions in patients with Alzheimer?s disease: a cross-sectional study
Vol. 3 No. 1 (2018), Original Article
Vol. 3 No. 1 (2018)

Potential drug interactions in patients with Alzheimer?s disease: a cross-sectional study

Original Article
https://doi.org/10.22563/2525-7323.2018.v3.n1.p.7-13
Published 2022-10-03
  • Gustavo Alves Andrade dos Santos
  • Claudinei Alves Santana
  • Paulo Celso Pardi
Gustavo Alves Andrade dos Santos
https://orcid.org/0000-0002-3326-5537
Claudinei Alves Santana
https://orcid.org/0000-0002-4593-6254
Paulo Celso Pardi
https://orcid.org/0000-0001-5903-6452
PDF - PORTUGUÊS (Português (Brasil))

Keywords

Alzheimer’s disease; drug interactions; anticholinesterase.

How to Cite

Alves Andrade dos Santos, G., Alves Santana, C., & Celso Pardi, P. (2022). Potential drug interactions in patients with Alzheimer?s disease: a cross-sectional study. JORNAL DE ASSISTÊNCIA FARMACÊUTICA E FARMACOECONOMIA, 3(1). https://doi.org/10.22563/2525-7323.2018.v3.n1.p.7-13
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Abstract

Background: Comorbidities in the elderly are especially common with advancing age when a series of physical and mental disorders occur simultaneously. Alzheimer’s disease is the most common form of dementia. Objective: To evaluate the main drug interactions present in the prescriptions of the elderly institutionalized in a geriatric institution. Method: Descriptive retrospective analytical study through the research in the medical records. Results: The medical prescriptions of 51 elderly patients were evaluated. We identified the risk of myopathy in patients receiving statins and the risk of increased QT interval in patients taking donepezil. Conclusion: Although under adequate treatment, elderly people with Alzheimer’s disease are highly susceptible to drug interactions, as a result of the variety of medications used in combination with anticholinesterases.

https://doi.org/10.22563/2525-7323.2018.v3.n1.p.7-13
PDF - PORTUGUÊS (Português (Brasil))

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